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A Peek Inside the Brains of ‘Super-Agers’
  + stars: | 2024-04-29 | by ( Dana G. Smith | ) www.nytimes.com   time to read: +1 min
When it comes to aging, we tend to assume that cognition gets worse as we get older. For a little over a decade, scientists have been studying a subset of people they call “super-agers.” These individuals are age 80 and up, but they have the memory ability of a person 20 to 30 years younger. Most research on aging and memory focuses on the other side of the equation — people who develop dementia in their later years. A paper published Monday in the Journal of Neuroscience helps shed light on what’s so special about the brains of super-agers. The biggest takeaway, in combination with a companion study that came out last year on the same group of individuals, is that their brains have less atrophy than their peers’ do.
Persons: that’s, we’re, , Emily Rogalski Organizations: University of Chicago, Neuroscience
How we change as we ageA decline in cognitive abilities is a normal part of healthy aging, said Dr. Emily Rogalski, Rosalind Franklin Professor of Neurology at the University of Chicago. A diagnosis of mild cognitive impairment is made clinically when cognitive difficulties become frequent and fall outside what is considered normal aging. “There’s not a whole lot of good evidence that there’s anything special about age 80 that leads to a drop-off” in cognitive abilities, Mather said. And they use cognitive tests, such as the Mini Mental Status Exam (MMSE) or Montreal Cognitive Assessment (MOCA), to assess performance in different cognitive areas. Although population-level data associates aging with cognitive decline, the actual manifestation of aging is very diverse on an individual level, Rogalski said.
Persons: Joe Biden, Donald Trump, Biden, Trump, Nikki Haley, Nancy Pelosi, Emily Rogalski, Rosalind Franklin, , Molly Mather, , Angela Roberts, Roberts, “ There’s, Mather, MMSE, We’re, ” Mather, Nir Barzilai, Rogalski, “ We’ve, superagers, Barzilai, “ It’s, Dr, Sanjay Gupta, ” Roberts Organizations: CNN, House, Republican, NBC, Neurology, University of Chicago, UCSF, Aging, Northwestern University’s Feinberg School of Medicine, National Institute, Western University, Institute for Aging Research, Albert Einstein College of Medicine, American Federation for Aging Research, Trump, Biden, Get CNN, CNN Health, Locations: Mexico, Egypt, Montreal
Siegler is a cognitive “SuperAger,” possessing a brain as sharp as people 20 to 30 years younger. She is part of an elite group enrolled in the Northwestern SuperAging Research Program, which has been studying the elderly with superior memories for 14 years. Once accepted, colorful 3D scans are taken of the brain and cognitive testing and brain scans are repeated every year or so. A SuperAger’s brain, usually donated to the research program by participants after death, also has bigger, healthier cells in the entorhinal cortex. SuperAger brains had three times fewer tau tangles, or abnormal formations of protein within nerve cells, than the brains of cognitively healthy controls, the study also found.
It was 1988, and he'd approached President Ronald Reagan in the Cabinet room at the White House. People scoffed at the glowing hourlong media conference that President Donald Trump's White House doctor gave about his health. Reagan publicly announced he had Alzheimer's disease five years after he left the White House. Francis Shen, who teaches psychiatry at Harvard Medical School's Center for Bioethics, would like to see information about political leaders' cognitive health made public. Cognitive health should be no different, he said, because it also might affect the way presidents and members of Congress make important decisions.
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